Compound Q&A
How is Methyl 1-(2-chloropyrimidin-4-yl)piperidine-4-carboxylate (CAS: 889126-33-4) typically synthesized?
Answer
Methyl 1-(2-chloropyrimidin-4-yl)piperidine-4-carboxylate (CAS: 889126-33-4) can be synthesized via a multi-step process involving the coupling of 4-chloropyrimidine with methyl piperidine-4-carboxylate. Commonly, this involves the use of a coupling reagent like 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to facilitate the amide bond formation. The reaction typically requires optimization for yield and selectivity.
About
CAS No
889126-33-4
English Name
Methyl 1-(2-chloropyrimidin-4-yl)piperidine-4-carboxylate
Molecular Formula
C11H14ClN3O2
Molecular Weight
255.7 g/mol
SMILES
COC(=O)C1CCN(CC1)C2=NC(=NC=C2)Cl
InChIKey
RANXPSAMFSXQAL-UHFFFAOYSA-N
Last Updated: 2026-01-07 10:18
