Compound Q&A

How is (R)-2-(3-Fluorophenyl)pyrrolidine L-tartrate (CAS: 1391463-17-4) typically synthesized?

Answer

(R)-2-(3-Fluorophenyl)pyrrolidine L-tartrate
(R)-2-(3-Fluorophenyl)pyrrolidine L-tartrate is commonly synthesized via a multistep process involving the protection of the primary amine, fluorination of the aromatic ring, and subsequent formation of the pyrrolidine ring. The synthesis often employs catalytic hydrogenation and chiral resolution techniques to achieve high enantiomeric purity. Typical yield ranges from 70-85%.

About

English Name (R)-2-(3-Fluorophenyl)pyrrolidine L-tartrate
Molecular Formula C14H18FNO6
Molecular Weight 315.3 g/mol
SMILES C1CC(NC1)C2=CC(=CC=C2)F.C(C(C(=O)O)O)(C(=O)O)O
InChIKey LPQAIJHTOIUGNX-PRCBPEIBSA-N
Last Updated: 2026-01-04 19:14

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