Compound Q&A

How is 4,5,6,7-Tetrahydro-2H-indazol-5-amine dihydrochloride (CAS: 74197-17-4) typically synthesized?

Answer

4,5,6,7-Tetrahydro-2H-indazol-5-amine dihydrochloride
4,5,6,7-Tetrahydro-2H-indazol-5-amine dihydrochloride can be synthesized by the condensation of indole with an appropriate aldehyde or ketone followed by reduction to form the tetrahydroindazole ring. The dihydrochloride salt is then obtained by protonation. Commonly, this synthesis involves the use of a Lewis acid catalyst like aluminium chloride to promote the condensation step, and sodium borohydride for reduction.

About

CAS No 74197-17-4
English Name 4,5,6,7-Tetrahydro-2H-indazol-5-amine dihydrochloride
Molecular Formula C7H13Cl2N3
Molecular Weight 210.11 g/mol
SMILES C1CC2=C(CC1N)C=NN2.Cl.Cl
InChIKey IHDUZMHOIVQJGL-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:06

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