Compound Q&A

How is Glycyrrhizin (CAS: 84775-66-6) typically synthesized?

Answer

Licorice, Glycyrrhiza glabra, ext.
Glycyrrhizin (CAS: 84775-66-6) is synthesized from the natural product glycyrrhizinic acid, often through hydrogenation of the unsaturated structure. Commonly, the synthesis involves catalytic hydrogenation over palladium or platinum catalysts, yielding high selectivity and good yield. This process is widely used in the production of glycyrrhizin for food and pharmaceutical applications.

About

CAS No 84775-66-6
English Name Licorice, Glycyrrhiza glabra, ext.
Molecular Formula C35H35NO14
Molecular Weight 693.65 g/mol
SMILES OCC1O[C@@H](OC2C=CC([C@@H]3CC(=O)C4C=CC(=CC=4O3)O)=CC=2)C(O[C@@H]2OCC(O)(COC(C3=CNC4=CC=CC=C34)=O)[C@@H]2O)[C@@H](O)[C@@H]1O
InChIKey GNJDLKNJCWOSBO-LKYFMKHGSA-N
Last Updated: 2026-01-01 20:06

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