Compound Q&A

How is Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9) typically synthesized?

Answer

Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate
Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9) is typically synthesized via a multi-step reaction involving condensation of benzofuran-2-carboxylic acid with ethyl chloroacetate followed by esterification. The reaction requires mild acidic or basic conditions and is known for its high yield and good selectivity. This compound is often used in the synthesis of functionalized derivatives and pharmaceutical intermediates.

About

CAS No 78917-44-9
English Name Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate
Molecular Formula C13H12O4
Molecular Weight 232.24 g/mol
SMILES CCOC(=O)CC(=O)C1=CC2=CC=CC=C2O1
InChIKey DBSJYHCDGBZOEP-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:05

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