Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate(CAS: 78917-44-9)

Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9) is a crystalline compound with a molecular weight of approximately 226.25 g/mol. The compound is slightly soluble in water but readily soluble in common organic solvents such as ethanol and acetone. It exhibits good reactivity towards nucleophiles and is commonly used in organic synthesis. The compound is stable under normal conditions but should be stored away from direct sunlight and moisture.

Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9) is typically synthesized via a multi-step reaction involving condensation of benzofuran-2-carboxylic acid with ethyl chloroacetate followed by esterification. The reaction requires mild acidic or basic conditions and is known for its high yield and good selectivity. This compound is often used in the synthesis of functionalized derivatives and pharmaceutical intermediates.

Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and functionalized compounds. Additionally, it has potential applications in the field of sensors and semiconductors due to its unique chemical properties.

When handling Ethyl 3-(1-benzofuran-2-yl)-3-oxopropanoate (CAS: 78917-44-9), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place and handled under a fume hood to minimize exposure. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.