Compound Q&A

How is Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate (CAS: 6974-10-3) typically synthesized?

Answer

Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate
Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate (CAS: 6974-10-3) is typically synthesized via the reaction of dioxoisoindoline and acetyl chloride under anhydrous conditions. This process involves condensation followed by acetylation, often catalyzed by an acid. The yield is generally 60-70%, and the reaction is carried out in a controlled manner to ensure high purity and selectivity.

About

CAS No 6974-10-3
English Name Ethyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate
Molecular Formula C12H11NO4
Molecular Weight 233.22 g/mol
SMILES CCOC(=O)CN1C(=O)C2=CC=CC=C2C1=O
InChIKey NYNCZOLNVTXTTP-UHFFFAOYSA-N
Last Updated: 2026-01-01 20:05

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