Compound Q&A
How is 4-(3-Fluorophenyl)-4-oxobutanoic acid (CAS: 69797-46-2) typically synthesized?
Answer
4-(3-Fluorophenyl)-4-oxobutanoic acid is typically synthesized via a multistep process involving the coupling of 3-fluorophenylacetyl chloride with phenylboronic acid followed by a hydrogenation step to introduce the oxo group. Common catalysts used include palladium on carbon, and the overall yield can be up to 70% with good selectivity. The reaction conditions should be carefully controlled to avoid side reactions and ensure high purity.
About
CAS No
69797-46-2
English Name
4-(3-Fluorophenyl)-4-oxobutanoic acid
Molecular Formula
C10H9FO3
Molecular Weight
196.18 g/mol
SMILES
C1=CC(=CC(=C1)F)C(=O)CCC(=O)O
InChIKey
HHVYNFFVNGZSNG-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34
