Compound Q&A
How is Lamotrigine EP Impurity D (CAS: 661463-79-2) typically synthesized?
Answer
Lamotrigine EP Impurity D (CAS: 661463-79-2) is synthesized through a series of reactions involving the transformation of tricyclic compounds. Common synthesis methods include the use of Lewis acids as catalysts, such as boron trifluoride, to facilitate ring-opening and subsequent rearrangements. The reaction typically yields a high purity product with a selectivity of over 95%, and the overall yield can reach up to 80%.
About
CAS No
661463-79-2
English Name
Lamotrigine EP Impurity D
Molecular Formula
C9H5Cl2N3O2
Molecular Weight
258.06 g/mol
SMILES
C1=CC(=C(C(=C1)Cl)Cl)C2=NNC(=O)NC2=O
InChIKey
JWSXBRQDWPGEPC-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34
