Compound Q&A
How is 4-(3-Methoxyphenyl)-1,3-thiazol-2-amine (CAS: 83558-37-6) typically synthesized?
Answer
4-(3-Methoxyphenyl)-1,3-thiazol-2-amine (CAS: 83558-37-6) can be synthesized via a multi-step process involving the condensation of 2-aminobenzothiazole with 3-methoxyaniline. Common methods include the use of coupling reagents like 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to enhance the coupling efficiency. The overall yield is typically around 70-80%, depending on the purity and conditions of the reactants.
About
CAS No
83558-37-6
English Name
4-(3-Methoxyphenyl)-1,3-thiazol-2-amine
Molecular Formula
C10H10N2OS
Molecular Weight
206.27 g/mol
SMILES
COC1=CC=CC(=C1)C2=CSC(=N2)N
InChIKey
NUMMWUVARLSQFR-UHFFFAOYSA-N
Last Updated: 2026-01-01 06:12
