Compound Q&A
How is 2-Chloro-N-(2-nitrophenyl)acetamide (CAS: 10147-70-3) typically synthesized?
Answer
2-Chloro-N-(2-nitrophenyl)acetamide (CAS: 10147-70-3) is typically synthesized by the reaction of 2-nitrophenyl acetate with hydrochloric acid. This synthesis involves the nucleophilic substitution of the hydroxyl group by chloride ion. The reaction yields a high purity product with a yield of around 75-80%. The use of appropriate solvents and temperature control can enhance the selectivity and yield of the reaction.
About
CAS No
10147-70-3
English Name
2-Chloro-N-(2-nitrophenyl)acetamide
Molecular Formula
C8H7ClN2O3
Molecular Weight
214.6 g/mol
SMILES
C1=CC=C(C(=C1)NC(=O)CCl)[N+](=O)[O-]
InChIKey
XXWVCPLQFJVURO-UHFFFAOYSA-N
Last Updated: 2026-01-01 06:12
