How is (E)-Naftifine (CAS: 65472-88-0) typically synthesized?

(E)-Naftifine is typically synthesized via a multi-step process involving the reaction of 2-naphthol with a ketone, followed by hydrogenation and subsequent functional group transformations. The reaction involves the use of a palladium catalyst and is carried out under optimized conditions to achieve high selectivity and yield. The process is complex and requires strict control over temperature and reaction time.