Compound Q&A

How is 5-Chloro-8-quinolinamine (CAS: 5432-09-7) typically synthesized?

Answer

5-Chloro-8-quinolinamine
5-Chloro-8-quinolinamine can be synthesized by the condensation of 8-hydroxyquinoline with thionyl chloride followed by hydrolysis. The key steps involve the formation of an intermediate chloro compound and subsequent hydrolysis to form the amine. This process is carried out under basic conditions with good yield and selectivity.

About

CAS No 5432-09-7
English Name 5-Chloro-8-quinolinamine
Molecular Formula C9H7ClN2
Molecular Weight 178.62 g/mol
SMILES C1=CC2=C(C=CC(=C2N=C1)N)Cl
InChIKey TVSJIVLFKNZFBJ-UHFFFAOYSA-N
Last Updated: 2025-12-31 21:15

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