Compound Q&A
How is (2Z)-4-(Benzylamino)-4-oxo-2-butenoic acid (CAS: 15329-69-8) typically synthesized?
Answer
(2Z)-4-(Benzylamino)-4-oxo-2-butenoic acid is usually synthesized via the condensation of benzylamine with acryloyl chloride in the presence of a base like triethylamine. The reaction gives good yield and selectivity, with the final product being isolated by recrystallization from appropriate solvents. This method ensures the formation of the correct isomer through the use of a suitable protecting group and selective conditions.
About
CAS No
15329-69-8
English Name
(2Z)-4-(Benzylamino)-4-oxo-2-butenoic acid
Molecular Formula
C11H11NO3
Molecular Weight
205.21 g/mol
SMILES
C1=CC=C(C=C1)CNC(=O)C=CC(=O)O
InChIKey
BHWGQIYJCMMSNM-SREVYHEPSA-N
Last Updated: 2025-12-31 16:28
