Compound Q&A
How is Secorapamycin A (CAS: 147438-27-5) typically synthesized?
Answer
Secorapamycin A is typically synthesized through a multistep reaction involving ring formation, acylation, and alkylation. Commonly used catalysts include phosphoryl chloride and triethylamine. The overall yield is moderate, around 50-60%, with high regioselectivity and stereoselectivity.
About
CAS No
147438-27-5
English Name
Secorapamycin A
Molecular Formula
C51H79NO13
Molecular Weight
914.19 g/mol
SMILES
C/C(=C\[C@@H](C)C(=O)/C=C/[C@H](C)C[C@H]1C[C@@H](OC)[C@H](O)CC1)/[C@@H](O)[C@@H](OC)C(=O)C(C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]1CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@H]1C(O)=O)OC
InChIKey
ZAVMPSVOEQNVCP-DLXZGSNXSA-N
Last Updated: 2025-12-31 16:27
