Compound Q&A
How is Leucine-enkephalin (CAS: 76622-26-9) typically synthesized?
Answer
Leucine-enkephalin (CAS: 76622-26-9) is typically synthesized through solid-phase peptide synthesis (SPPS). The synthesis involves the stepwise addition of amino acids to a growing peptide chain on a solid support, with appropriate protecting groups. Commonly used coupling agents include DCC (dicyclohexylcarbodiimide) and HOBt (1-hydroxybenzotriazole). The yield is typically around 70-80%, with good selectivity towards the desired product.
About
CAS No
76622-26-9
English Name
Leucine-enkephalin, arg-arg-val-gly-arg-pro-glu-trp-trp-met-asp-tyr-gly-
Molecular Formula
C130H184N38O31S2
Molecular Weight
2839.2 g/mol
SMILES
CC(C)C(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC6=CC=C(C=C6)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC7=CC=C(C=C7)O)C(=O)NCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCSC)NC(=O)C(CC8=CC=CC=C8)NC(=O)CNC(=O)CNC(=O)C(CC9=CC=C(C=C9)O)N
InChIKey
QYDAFJUKVGVEKO-PKOVDKIBSA-N
Last Updated: 2025-12-31 11:48
