Compound Q&A
How is (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-phenyl-2-sulfoacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (CAS: 41744-40-5) typically synthesized?
Answer
![(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-phenyl-2-sulfoacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid](https://static.chemtradehub.com/structs/417/41744-40-5-b3c3.webp "(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-phenyl-2-sulfoacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid")
The compound is synthesized through a multi-step process involving amidation and sulfonation reactions. Key steps include the preparation of the sulfoacetyl derivative of the phenyl group, followed by amidation with the azabicyclic amine. The reaction is typically conducted in the presence of an acid catalyst and requires precise control of temperature and reaction time to achieve high yield and selectivity.
About
CAS No
41744-40-5
English Name
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-phenyl-2-sulfoacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular Formula
C16H18N2O7S2
Molecular Weight
414.46 g/mol
SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)S(=O)(=O)O)C(=O)O)C
InChIKey
JETQIUPBHQNHNZ-NJBDSQKTSA-N
Last Updated: 2025-12-31 06:49
![(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-phenyl-2-sulfoacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid — Hubei Yangxin Pharmaceutical Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}