Compound Q&A
How is 3-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride (CAS: 875167-01-4) typically synthesized?
Answer
3-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride is typically synthesized via the sulfonation of 3-chloro-5-(trifluoromethyl)benzene using concentrated sulfuric acid. The reaction is conducted in a fume hood to manage the volatile gases produced. The product is then chlorosulfonated, often using thionyl chloride, to generate the sulfonate chloride. The process requires careful control of temperature and concentration to achieve high yield and selectivity.
About
CAS No
875167-01-4
English Name
3-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride
Molecular Formula
C7H3Cl2F3O2S
Molecular Weight
279.07 g/mol
SMILES
FC(F)(F)c1cc(Cl)cc(c1)S(=O)(=O)Cl
InChIKey
JYUGVORTFRFETG-UHFFFAOYSA-N
Last Updated: 2025-12-31 06:49
