Compound Q&A
How is (2S)-2-amino-3-(1-benzyl-1H-imidazol-4-yl)propanoic acid (CAS: 16832-24-9) typically synthesized?
Answer
The synthesis of (2S)-2-amino-3-(1-benzyl-1H-imidazol-4-yl)propanoic acid (CAS: 16832-24-9) is typically achieved via a multistep process. Starting from 1-benzyl-1H-imidazole and glycine, the reaction proceeds through condensation followed by amidation. This process involves the use of coupling agents like HATU or EDC and a suitable base like DIPEA. The yield is usually around 70-80%, and the product can be purified by column chromatography or recrystallization.
About
CAS No
16832-24-9
English Name
(2S)-2-amino-3-(1-benzyl-1H-imidazol-4-yl)propanoic acid
Molecular Formula
C13H15N3O2
Molecular Weight
245.28 g/mol
SMILES
C1=CC=C(C=C1)CN2C=C(N=C2)CC(C(=O)O)N
InChIKey
NMXSWQMJOZUQKY-LBPRGKRZSA-N
Last Updated: 2025-12-29 01:16
