Compound Q&A
How is (5-Chloro-2-methyl-1H-indol-3-yl)acetic acid (CAS: 19017-52-8) typically synthesized?
Answer
(5-Chloro-2-methyl-1H-indol-3-yl)acetic acid is synthesized through the acetylation of 5-chloro-2-methyl-1H-indole using acetic anhydride in the presence of a catalytic amount of pyridine. The method involves mild heating and purification by recrystallization from ethanol. This synthesis yields a product with excellent purity and selectivity.
About
CAS No
19017-52-8
English Name
(5-Chloro-2-methyl-1H-indol-3-yl)acetic acid
Molecular Formula
C11H10ClNO2
Molecular Weight
223.65899999999996 g/mol
SMILES
CC1=C(C2=C(N1)C=CC(=C2)Cl)CC(=O)O
InChIKey
OAIODEZFMSXHFQ-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
