Compound Q&A
How is Methyl 3-(5-hydroxy-2-pyrimidinyl)benzoate (CAS: 1092568-87-0) typically synthesized?
Answer
Methyl 3-(5-hydroxy-2-pyrimidinyl)benzoate (CAS: 1092568-87-0) is typically synthesized by the condensation of 5-hydroxy-2-pyrimidinone with methyl benzoate in the presence of a catalyst such as p-toluenesulfonic acid (PTSA). The reaction yields a mixture that can be purified by recrystallization. The yield is generally around 70-80%, and the method is selective for the desired product.
About
CAS No
1092568-87-0
English Name
Methyl 3-(5-hydroxy-2-pyrimidinyl)benzoate
Molecular Formula
C12H10N2O3
Molecular Weight
230.22 g/mol
SMILES
COC(=O)c1cccc(c1)c2ncc(cn2)O
InChIKey
HMOOJGNQBDDOPX-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
