Compound Q&A
How is 5-Methyl-2-(tributylstannyl)-1,3-thiazole (CAS: 848613-91-2) typically synthesized?
Answer
5-Methyl-2-(tributylstannyl)-1,3-thiazole is synthesized via the coupling of tributyltin chloride with 1,3-thiazole-2-carbaldehyde in the presence of a Lewis acid catalyst, such as zinc chloride. The reaction is conducted at a moderate temperature, and the product is isolated by column chromatography. The selectivity and yield are influenced by the choice of catalyst and reaction conditions, with typical yields around 70-80%.
About
CAS No
848613-91-2
English Name
5-Methyl-2-(tributylstannyl)-1,3-thiazole
Molecular Formula
C16H31NSSn
Molecular Weight
388.21 g/mol
SMILES
CCCC[Sn](CCCC)(CCCC)C1=NC=C(S1)C
InChIKey
LALGELPHLJBAEK-UHFFFAOYSA-N
Last Updated: 2025-12-25 13:43
