Compound Q&A
How is Tert-butyl 1,2,3,4-tetrahydroisoquinolin-7-ylcarbamate (CAS: 885270-54-2) typically synthesized?
Answer
Tert-butyl 1,2,3,4-tetrahydroisoquinolin-7-ylcarbamate is typically synthesized via a multi-step process involving the condensation of tert-butyl isonicotinate with 1,2,3,4-tetrahydroisoquinoline under basic conditions. The reaction is catalyzed by an appropriate base such as triethylamine. The yield is generally around 70%, and the product is isolated by recrystallization from solvents like DMF.
About
CAS No
885270-54-2
English Name
Tert-butyl 1,2,3,4-tetrahydroisoquinolin-7-ylcarbamate
Molecular Formula
C14H20N2O2
Molecular Weight
248.33 g/mol
SMILES
CC(C)(C)OC(=O)NC1=CC2=C(CCNC2)C=C1
InChIKey
VTTOWYHROSNYPM-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48
