Compound Q&A

How is (R)-Bis[(S)-1-phenylethyl]amine (CAS: 56210-72-1) typically synthesized?

Answer

(?)-Bis[(S)-1-phenylethyl]amine
(R)-Bis[(S)-1-phenylethyl]amine (CAS: 56210-72-1) can be synthesized via a multistep process involving the coupling of phenylethyl bromide with (S)-1-phenylethanol. This reaction typically uses a palladium catalyst and a base such as potassium carbonate. The product is isolated through phase separation and purified by recrystallization. The overall yield is approximately 70-75%.

About

CAS No 56210-72-1
English Name (?)-Bis[(S)-1-phenylethyl]amine
Molecular Formula C16H19N
Molecular Weight 225.33 g/mol
SMILES CC(C1=CC=CC=C1)NC(C)C2=CC=CC=C2
InChIKey NXLACVVNHYIYJN-KBPBESRZSA-N
Last Updated: 2025-12-25 08:48

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