Compound Q&A
How is 2,5,6-Trichloronicotinamide (CAS: 142266-62-4) typically synthesized?
Answer
2,5,6-Trichloronicotinamide is typically synthesized via the condensation of chlorobenzoyl chloride with hydrazine hydrate followed by heating. The reaction is catalyzed by a Lewis acid such as aluminum chloride. This method provides a yield of around 70-80%, with good selectivity towards the desired product. The process is conducted under an inert atmosphere to avoid side reactions.
About
CAS No
142266-62-4
English Name
2,5,6-Trichloronicotinamide
Molecular Formula
C6H3Cl3N2O
Molecular Weight
225.46 g/mol
SMILES
c1c(c(nc(c1Cl)Cl)Cl)C(=O)N
InChIKey
DBAVDGXPOXFHRC-UHFFFAOYSA-N
Last Updated: 2025-12-25 08:48
