Compound Q&A

How is 2,8-Dimethyl-4(1H)-quinolinone (CAS: 15644-80-1) typically synthesized?

Answer

2,8-Dimethyl-4(1H)-quinolinone
2,8-Dimethyl-4(1H)-quinolinone (CAS: 15644-80-1) can be synthesized via a condensation reaction of 2,4-dimethylquinoline with acetic anhydride. The synthesis typically involves heating the reactants under mild conditions to allow the formation of the quinolinone ring. The reaction yield is around 75-80%, and the use of azeotropic distillation can improve the purity of the product. Commonly, no catalyst is required for this reaction.

About

CAS No 15644-80-1
English Name 2,8-Dimethyl-4(1H)-quinolinone
Molecular Formula C11H11NO
Molecular Weight 173.21 g/mol
SMILES CC1=C2C(=CC=C1)C(=O)C=C(N2)C
InChIKey QUHJYDMHDWSZIP-UHFFFAOYSA-N
Last Updated: 2025-12-25 04:58

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