Compound Q&A

How is 4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol (CAS: 4263-88-1) typically synthesized?

Answer

4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
This compound can be synthesized via a multi-step process involving the condensation of 3-methoxy-4-hydroxybenzaldehyde with 6-(3-methoxy-4-hydroxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan. The synthesis typically requires the use of a strong base such as sodium hydride and needs to be conducted in an inert atmosphere to prevent side reactions. Careful control of reaction conditions is necessary to achieve high yields and selectivity.

About

CAS No 4263-88-1
English Name 4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
Molecular Formula C20H22O6
Molecular Weight 358.39 g/mol
SMILES COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O
InChIKey HGXBRUKMWQGOIE-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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