4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol(CAS: 4263-88-1)

4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol is a crystalline solid with a molecular weight of approximately 427.45 g/mol. It has a pKa of around 9.0 and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo esterification and etherification reactions. It is also prone to oxidation under certain conditions.

This compound can be synthesized via a multi-step process involving the condensation of 3-methoxy-4-hydroxybenzaldehyde with 6-(3-methoxy-4-hydroxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan. The synthesis typically requires the use of a strong base such as sodium hydride and needs to be conducted in an inert atmosphere to prevent side reactions. Careful control of reaction conditions is necessary to achieve high yields and selectivity.

4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol is primarily used in the pharmaceutical and chemical industries. It serves as a precursor for the synthesis of various drug compounds and is also used in the development of new materials and sensors. Its unique chemical properties make it suitable for applications in semiconductors and other advanced materials.

When handling 4-[6-(4-Hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. The substance should be handled in a fume hood to minimize exposure to air and avoid inhalation. Proper spill cleanup procedures should be followed, and the material safety data sheet (MSDS) should be consulted for specific guidelines. Storage should be in a cool, dry place away from direct sunlight and heat sources.