Compound Q&A
How is Diethyl 2,5-dioxobicyclo[2.2.2]octane-1,4-dicarboxylate (CAS: 843-59-4) typically synthesized?
Answer
![Diethyl 2,5-dioxobicyclo[2.2.2]octane-1,4-dicarboxylate](https://static.chemtradehub.com/structs/843/843-59-4-ee18.webp "Diethyl 2,5-dioxobicyclo[2.2.2]octane-1,4-dicarboxylate")
Diethyl 2,5-dioxobicyclo[2.2.2]octane-1,4-dicarboxylate (CAS: 843-59-4) is commonly synthesized via a multi-step process involving the condensation of 2,5-dibromobicyclo[2.2.2]octane with diethylmalonate. This method typically involves the use of a base like sodium hydride and yields up to 85% of the desired product. The reaction is typically carried out under an inert atmosphere to prevent unwanted side reactions.
About
CAS No
843-59-4
English Name
Diethyl 2,5-dioxobicyclo[2.2.2]octane-1,4-dicarboxylate
Molecular Formula
C14H18O6
Molecular Weight
282.29 g/mol
SMILES
CCOC(=O)C12CCC(C(=O)C1)(CC2=O)C(=O)OCC
InChIKey
ZRMZQKZRZQCGJV-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29
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