Compound Q&A
How is 6-Chloro-2-quinolinecarboxylic acid (CAS: 59394-30-8) typically synthesized?
Answer
6-Chloro-2-quinolinecarboxylic acid (CAS: 59394-30-8) is typically synthesized via the condensation of 2-quinolinecarboxylic acid with thionyl chloride in the presence of a base like triethylamine. The reaction proceeds through an acyl chloride intermediate, followed by acidification to yield the desired acid. The yield is generally good, around 85-90%, with minimal by-products.
About
CAS No
59394-30-8
English Name
6-Chloro-2-quinolinecarboxylic acid
Molecular Formula
C10H6ClNO2
Molecular Weight
207.62 g/mol
SMILES
C1=CC2=C(C=CC(=N2)C(=O)O)C=C1Cl
InChIKey
UKMWQYNJAVNCOZ-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29
