Compound Q&A
How is Tetramethylrhodamine-5-isothiocyanate (CAS: 80724-19-2) typically synthesized?
Answer
Tetramethylrhodamine-5-isothiocyanate is typically synthesized by reacting tetramethylrhodamine with carbonic anhydride. The reaction is carried out in an inert atmosphere to prevent decomposition. The yield is around 90%, and the product is isolated by column chromatography. No specific catalysts are required for this synthesis.
About
CAS No
80724-19-2
English Name
Tetramethylrhodamine-5-isothiocyanate
Molecular Formula
C25H21N3O3S
Molecular Weight
443.52 g/mol
SMILES
CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=C(C=C4)N=C=S)C(=O)[O-]
InChIKey
IJSMFQNTEUNRPY-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31
