Compound Q&A

How is 1-[2-(4-Morpholinyl)ethyl]-3-(4-{(2E)-3-[6-(4-morpholinyl)-2-pyridinyl]-2-propenoyl}phenyl)urea (CAS: 867164-40-7) typically synthesized?

Answer

1-[2-(4-Morpholinyl)ethyl]-3-(4-{(2E)-3-[6-(4-morpholinyl)-2-pyridinyl]-2-propenoyl}phenyl)urea
This compound is typically synthesized via a multistep process involving the reaction of 2-(4-morpholinylethyl)amine with 4-(2-propenoyl)-6-(4-morpholinyl)-2-pyridone. The synthesis requires careful control of reaction conditions, including temperature and pH, to achieve high yield and selectivity. Commonly used catalysts include Lewis acids or transition metal complexes.

About

English Name 1-[2-(4-Morpholinyl)ethyl]-3-(4-{(2E)-3-[6-(4-morpholinyl)-2-pyridinyl]-2-propenoyl}phenyl)urea
Molecular Formula C25H31N5O4
Molecular Weight 465.55 g/mol
SMILES O=C(NCCN1CCOCC1)NC1=CC=C(C=C1)C(=O)C=CC1=NC(=CC=C1)N1CCOCC1
InChIKey SQTSPANZQDCPLB-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31

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