Compound Q&A
How is 3-Iodo-4-isopropylbenzoic acid (CAS: 99059-64-0) typically synthesized?
Answer
3-Iodo-4-isopropylbenzoic acid is commonly synthesized through alkylation of 4-isopropylbenzoic acid with iodomethane, followed by iodination of the resulting product using sodium iodide in the presence of a base like sodium hydroxide. The reaction is typically carried out in a solvent such as dimethylformamide (DMF) at room temperature. The product is isolated by crystallization and recrystallization to obtain high purity.
About
CAS No
99059-64-0
English Name
3-Iodo-4-isopropylbenzoic acid
Molecular Formula
C10H11IO2
Molecular Weight
290.1 g/mol
SMILES
CC(C)C1=C(C=C(C=C1)C(=O)O)I
InChIKey
YKYRHJJXCOILPA-UHFFFAOYSA-N
Last Updated: 2025-11-27 19:31
