What are the physical and chemical properties of Avatrombopag Impurity 8 (CAS: 570407-42-0)?

Avatrombopag Impurity 8 is a crystalline solid with a molecular weight of approximately 419.45 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetonitrile. The impurity is chemically reactive and can undergo ring-opening reactions under basic conditions. It is less stable compared to the parent compound, making it important to store under an inert atmosphere to prevent degradation.