Compound Q&A
How is (6-(4-Methylpiperazin-1-yl)pyridin-3-yl)boronic acid (CAS: 936353-84-3) typically synthesized?
Answer
(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)boronic acid is typically synthesized via a multistep process involving the preparation of 4-methylpiperazin-1-yl derivative and subsequent coupling with 3-pyridylboronic acid. The synthesis usually requires the use of a palladium catalyst, such as Pd(PPh3)4, and a base like triethylamine. The yield is generally around 70-80%, with excellent selectivity towards the boronic ester formation.
About
CAS No
936353-84-3
English Name
(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)boronic acid
Molecular Formula
C10H16BN3O2
Molecular Weight
221.07 g/mol
SMILES
B(C1=CN=C(C=C1)N2CCN(CC2)C)(O)O
InChIKey
YGZOCDXCJWHNQN-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33
