Compound Q&A

How is Ethyl 6-(hydroxymethyl)-2-pyridinecarboxylate (CAS: 41337-81-9) typically synthesized?

Answer

Ethyl 6-(hydroxymethyl)-2-pyridinecarboxylate
Ethyl 6-(hydroxymethyl)-2-pyridinecarboxylate is commonly synthesized via reductive amination of 2-pyridinecarboxaldehyde with ethylamine in the presence of a reducing agent like sodium borohydride. The reaction is performed under mild conditions to ensure high selectivity and yield. Catalysts such as sodium hydroxide are also used to achieve optimal results.

About

CAS No 41337-81-9
English Name Ethyl 6-(hydroxymethyl)-2-pyridinecarboxylate
Molecular Formula C9H11NO3
Molecular Weight 181.19099999999997 g/mol
SMILES CCOC(=O)C1=CC=CC(=N1)CO
InChIKey CDFOARSBQKJGNL-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:32

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