Compound Q&A

How is 1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9) typically synthesized?

Answer

1-Fluoro-2-iodo-4-nitrobenzene
1-Fluoro-2-iodo-4-nitrobenzene (CAS: 177363-10-9) can be synthesized via a multistep process involving the iodination of 1-fluoro-4-nitrobenzene followed by nitration. Common reagents include iodine in the presence of base and nitric acid. The synthesis typically yields about 70-80% of the desired product with good selectivity for the 2-iodo position.

About

English Name 1-Fluoro-2-iodo-4-nitrobenzene
Molecular Formula C6H3FINO2
Molecular Weight 266.9964 g/mol
SMILES C1=CC(=C(C=C1[N+](=O)[O-])I)F
InChIKey XSFIPDPCQOJJFR-UHFFFAOYSA-N
Last Updated: 2025-11-07 12:11

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