Compound Q&A
How is (6-chloro-2-fluoro-3-methoxy-phenyl)boronic acid (CAS: 867333-04-8) typically synthesized?
Answer
(6-Chloro-2-fluoro-3-methoxy-phenyl)boronic acid can be synthesized using a two-step process involving the protection of the methoxy group, followed by boronation with a boronic ester. Commonly, the synthesis involves the use of a palladium catalyst and a phase transfer catalyst. The yield is typically around 70-80%, with good selectivity towards the desired product.
About
CAS No
867333-04-8
English Name
(6-chloro-2-fluoro-3-methoxy-phenyl)boronic acid
Molecular Formula
C7H7BClFO3
Molecular Weight
204.39 g/mol
SMILES
B(C1=C(C=CC(=C1F)OC)Cl)(O)O
InChIKey
CVKDGGIRBCXOSZ-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
