Compound Q&A
How is Methyl 2,5-difluoro-4-nitrobenzoate (CAS: 924868-81-5) typically synthesized?
Answer
Methyl 2,5-difluoro-4-nitrobenzoate is usually synthesized by nitration of 2,5-difluorobenzoic acid using nitric acid in a suitable solvent like acetic anhydride. The reaction is typically conducted under reflux conditions. Catalysts such as concentrated sulfuric acid are used to enhance the selectivity and yield of the desired product.
About
CAS No
924868-81-5
English Name
Methyl 2,5-difluoro-4-nitrobenzoate
Molecular Formula
C8H5F2NO4
Molecular Weight
217.13 g/mol
SMILES
COC(=O)C1=CC(=C(C=C1F)[N+](=O)[O-])F
InChIKey
XBUVRWIIEREYFL-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
