Compound Q&A
How is Methyl 2,3-dichloroquinoxaline-6-carboxylate (CAS: 108258-54-4) typically synthesized?
Answer
Methyl 2,3-dichloroquinoxaline-6-carboxylate can be synthesized via the condensation of 2,3-dichloroquinoxaline with methyl acetoacetate in the presence of a suitable catalyst such as p-toluenesulfonic acid. The reaction yields a mixture of diastereomers, but the desired product can be isolated through recrystallization. The yield is typically around 70-80%.
About
CAS No
108258-54-4
English Name
Methyl 2,3-dichloroquinoxaline-6-carboxylate
Molecular Formula
C10H6Cl2N2O2
Molecular Weight
257.076 g/mol
SMILES
COC(=O)C1=CC2=C(C=C1)N=C(C(=N2)Cl)Cl
InChIKey
ZLWYANCDEVPWLW-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
