Compound Q&A
How is 2-Bromo-4-chlorothieno[3,2-c]pyridine (CAS: 28948-61-0) typically synthesized?
Answer
![2-Bromo-4-chlorothieno[3,2-c]pyridine](https://static.chemtradehub.com/structs/289/28948-61-0-bf5c.webp "2-Bromo-4-chlorothieno[3,2-c]pyridine")
2-Bromo-4-chlorothieno[3,2-c]pyridine is commonly synthesized via the substitution of chlorine with bromine on the thieno[3,2-c]pyridine ring. This is typically achieved using bromine in the presence of a base such as sodium hydride in an anhydrous solvent like DMF. The reaction is selective and yields high purity product with good recovery rates.
About
CAS No
28948-61-0
English Name
2-Bromo-4-chlorothieno[3,2-c]pyridine
Molecular Formula
C7H3BrClNS
Molecular Weight
248.53 g/mol
SMILES
C1=CN=C(C2=C1SC(=C2)Br)Cl
InChIKey
QPGCPWZFCLBFCG-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
![2-Bromo-4-chlorothieno[3,2-c]pyridine — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![2-Bromo-4-chlorothieno[3,2-c]pyridine — ShangHaiJiZhiShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecbee2b2de6e8e95a5b72/67cecbee2b2de6e8e95a5b72-logo.webp){kind=logo}
![2-Bromo-4-chlorothieno[3,2-c]pyridine — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![2-Bromo-4-chlorothieno[3,2-c]pyridine — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}