How is Methyl 4-iodo-3-methoxybenzoate (CAS: 35387-92-9) typically synthesized?

Methyl 4-iodo-3-methoxybenzoate can be synthesized through a series of steps, starting from methyl 3-methoxybenzoate. The key steps involve the introduction of the iodine atom, typically via a nucleophilic substitution reaction with iodine in the presence of a base. This reaction is sensitive to conditions and requires careful control of the temperature and reaction time to achieve high yield and selectivity.