Compound Q&A
How is 1-(3-Fluoro-4-nitrophenyl)ethanone (CAS: 72802-25-6) typically synthesized?
Answer
1-(3-Fluoro-4-nitrophenyl)ethanone is typically synthesized by nitration of 1-(3-fluorophenyl)ethanone. The nitration reaction is carried out in the presence of a strong acid, such as sulfuric acid, and nitric acid. The reaction is exothermic and requires careful temperature control to ensure selectivity and yield. Common solvents used include acetic anhydride or acetic acid, with water as the inorganic acid source.
About
CAS No
72802-25-6
English Name
1-(3-Fluoro-4-nitrophenyl)ethanone
Molecular Formula
C8H6FNO3
Molecular Weight
183.1365 g/mol
SMILES
CC(=O)C1=CC(=C(C=C1)[N+](=O)[O-])F
InChIKey
UHAATBAYLFRWMR-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
