Compound Q&A
How is 2,2,3,3-Tetrafluoropropyl 4-methylbenzenesulfonate (CAS: 786-31-2) typically synthesized?
Answer
2,2,3,3-Tetrafluoropropyl 4-methylbenzenesulfonate is typically synthesized through the sulfonation of 4-methylbenzenesulfonic acid with 2,2,3,3-tetrafluoropropyl bromide. This process usually requires the use of a Lewis acid catalyst such as aluminum chloride to promote the electrophilic aromatic substitution. The yield of the reaction is moderate, around 60-70%, and the selectivity is high, ensuring the formation of the desired product.
About
CAS No
786-31-2
English Name
2,2,3,3-Tetrafluoropropyl 4-methylbenzenesulfonate
Molecular Formula
C10H10F4O3S
Molecular Weight
286.25 g/mol
SMILES
CC1=CC=C(C=C1)S(=O)(=O)OCC(C(F)F)(F)F
InChIKey
IMDNPHAMGJIKNV-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
