Compound Q&A

How is 1,4-Phenylenebis[(4-fluorophenyl)methanone] (CAS: 68418-51-9) typically synthesized?

Answer

1,4-Phenylenebis[(4-fluorophenyl)methanone]
1,4-Phenylenebis[(4-fluorophenyl)methanone] is typically synthesized via the condensation of 4-fluoro-phenylacetic acid with 1,4-dibromobenzene using a base like sodium hydride as a catalyst. The reaction yields good selectivity and is known to provide high yields. The process involves heating the reaction mixture under an inert atmosphere to ensure the formation of the desired product.

About

CAS No 68418-51-9
English Name 1,4-Phenylenebis[(4-fluorophenyl)methanone]
Molecular Formula C20H12F2O2
Molecular Weight 220.22 g/mol
SMILES C1=CC(=CC=C1C(=O)C2=CC=C(C=C2)F)C(=O)C3=CC=C(C=C3)F
InChIKey LLJNTLUXOZPFQB-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33

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