Compound Q&A
How is 5,5'-Bis(trifluoromethyl)-2,2'-bipyridine (CAS: 142946-80-3) typically synthesized?
Answer
5,5'-Bis(trifluoromethyl)-2,2'-bipyridine is synthesized by the coupling of 2,2'-bipyridine with trifluoromethylating agents such as trifluoromethyl chlorides in the presence of a suitable catalyst. The reaction proceeds with good yield and selectivity, making it a reliable method for large-scale production.
About
CAS No
142946-80-3
English Name
5,5'-Bis(trifluoromethyl)-2,2'-bipyridine
Molecular Formula
C12H6F6N2
Molecular Weight
292.18 g/mol
SMILES
FC(C1=CN=C(C2=NC=C(C(F)(F)F)C=C2)C=C1)(F)F
InChIKey
ZHMXQYAUGQASQM-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
