5,5'-Bis(trifluoromethyl)-2,2'-bipyridine(CAS: 142946-80-3)

5,5'-Bis(trifluoromethyl)-2,2'-bipyridine is a crystalline solid with a high molecular weight. It is moderately soluble in common organic solvents like DMSO and DMF. The compound is known for its high stability and low reactivity under normal conditions, making it suitable for a variety of applications in research and industry.

5,5'-Bis(trifluoromethyl)-2,2'-bipyridine is synthesized by the coupling of 2,2'-bipyridine with trifluoromethylating agents such as trifluoromethyl chlorides in the presence of a suitable catalyst. The reaction proceeds with good yield and selectivity, making it a reliable method for large-scale production.

5,5'-Bis(trifluoromethyl)-2,2'-bipyridine finds applications in pharmaceuticals, where it is used as an intermediate in the synthesis of new drugs. It is also utilized in the development of sensors, semiconductors, and polymers due to its unique electronic properties.

When handling 5,5'-Bis(trifluoromethyl)-2,2'-bipyridine, it is recommended to use personal protective equipment (PPE) such as gloves and goggles. This compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of spill, follow the safety data sheet (SDS) guidelines for cleanup and disposal.