Compound Q&A

How is 4-Methyl-2-(trifluoromethyl)aniline (CAS: 87617-23-0) typically synthesized?

Answer

4-Methyl-2-(trifluoromethyl)aniline
4-Methyl-2-(trifluoromethyl)aniline can be synthesized through the nitration of 4-methyl-2-methoxybenzene followed by reduction of the nitro group to an amino group. The reaction is typically catalyzed by sulfuric acid and performed in the presence of water. The yield ranges from 70% to 80%, and the process involves careful control of temperature and reagent concentration to ensure selectivity.

About

CAS No 87617-23-0
English Name 4-Methyl-2-(trifluoromethyl)aniline
Molecular Formula C8H8F3N
Molecular Weight 175.15 g/mol
SMILES CC1=CC(=C(C=C1)N)C(F)(F)F
InChIKey JPPWLYYUBCTQMY-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23

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