Compound Q&A
How is 3-(Trifluoromethyl)dibenzo[b,e]oxepin-11(6H)-one (CAS: 4504-94-3) typically synthesized?
Answer
![3-(Trifluoromethyl)dibenzo[b,e]oxepin-11(6H)-one](https://static.chemtradehub.com/structs/450/4504-94-3-b60c.webp "3-(Trifluoromethyl)dibenzo[b,e]oxepin-11(6H)-one")
3-(Trifluoromethyl)dibenzo[b,e]oxepin-11(6H)-one can be synthesized via a multistep reaction involving the condensation of 3-(trifluoromethyl)acrylic acid and vicinal ketals, followed by ring closure and subsequent dehydration. This process often requires the use of Lewis acids as catalysts and typically yields up to 80% purity.
About
CAS No
4504-94-3
English Name
3-(Trifluoromethyl)dibenzo[b,e]oxepin-11(6H)-one
Molecular Formula
C15H9F3O2
Molecular Weight
278.23 g/mol
SMILES
O=C1c2ccc(cc2OCc2c1cccc2)C(F)(F)F
InChIKey
LJXVSEITOIGFPP-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23
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