How is 3'-Deoxycytidine (CAS: 7057-33-2) typically synthesized?

3'-Deoxycytidine is typically synthesized via nucleobase modification of cytidine. A common method involves the use of a deoxycytidine-5'-monophosphate derivative as a starting material. The synthesis often employs catalytic amounts of a suitable base, such as sodium hydride, to facilitate the deoxygenation at the 3'-position. The yield and selectivity can be optimized through careful control of reaction conditions.